Disease: Malignant neoplasm of larynx
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TOPBP1 Q92547 DNA topoisomerase II binding protein 1 1.00 0.644 0.692
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
RECQL5 O94762 RecQ like helicase 5 Enzyme 3.2E-18 0.682 0.500
RECQL P46063 RecQ like helicase Enzyme 1.5E-20 0.615 0.615
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PDLIM7 Q9NR12 PDZ and LIM domain 7 Cellular structure 0.71 0.474 0.808
NLRP2 Q9NX02 NLR family pyrin domain containing 2 1.4E-38 0.515 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MIR27A microRNA 27a 0.466 0.846
MIR21 microRNA 21 0.363 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923